Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393648 | 0.89 | LMNA (0.58) | PREPALDH1A1LMNASMN1; SMN2F13A1 | |
| SCHEMBL9260332 | 0.88 | ALDH1A1 (0.49) | PREPALDH1A1LMNASMN1; SMN2F13A1 | |
| SCHEMBL6601889 | 0.88 | ALDH1A1 (0.49) | PREPALDH1A1LMNASMN1; SMN2F13A1 | |
| SCHEMBL30732657 | 0.87 | ALDH1A1 (0.49) | PREPALDH1A1LMNASMN1; SMN2F13A1 | |
| SCHEMBL29652185 | 0.84 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2F13A1TGM2 | |
| SCHEMBL14451403 | 0.84 | LMNA (0.52) | ALDH1A1LMNASMN1; SMN2F13A1TGM2 | |
| SCHEMBL8029231 | 0.84 | ALDH1A1 (0.61) | PREPALDH1A1LMNASMN1; SMN2F13A1 | |
| SCHEMBL8395084 | 0.84 | ALDH1A1 (0.58) | PREPALDH1A1LMNASMN1; SMN2F13A1 | |
| SCHEMBL3947244 | 0.83 | LMNA (0.51) | ALDH1A1LMNASMN1; SMN2F13A1TGM2 | |
| SCHEMBL14009946 | 0.83 | LMNA (0.51) | ALDH1A1LMNASMN1; SMN2F13A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001774-A1 | Derivatives of BPTI (basic pancreatic trypsin-inhibitor), process for their preparation and their use as medicines | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |