Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669404 | 0.79 | S100A4 (0.37) | MEN1KMT2AMAPTTRPV1 | |
| SCHEMBL27695100 | 0.76 | KMT2A (0.62) | MEN1KMT2AMAPTLMNACA1 | |
| SCHEMBL8030507 | 0.76 | TSHR (0.52) | MEN1KMT2AMAPTGAAALOX5 | |
| SCHEMBL28187810 | 0.76 | LMNA (0.39) | MEN1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL399101 | 0.76 | TRPV1 (0.43) | MEN1KMT2AMAPTEGFRLMNA | |
| SCHEMBL8061244 | 0.76 | ALDH1A1 (0.52) | MEN1KMT2AMAPTLMNAGAA | |
| SCHEMBL6199248 | 0.76 | ALDH1A1 (0.52) | MEN1KMT2AMAPTEGFRLMNA | |
| SCHEMBL4853551 | 0.76 | ALDH1A1 (0.52) | MEN1KMT2AMAPTLMNACA14 | |
| Nitric Acid SCHEMBL20984383 | 0.76 | IDO1 (0.49) | MEN1KMT2AMAPTEGFRLMNA | |
| Hydrochloric Acid SCHEMBL28403396 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| EP-0003881-A1 | Substituted phenylnitramines, their preparation and their application as fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4130645-A | Fungicidal phenylnitramines and new phenylnitramines | AMERICAN CYANAMID COMPANY (US) | 1978-12-19 | — | — | US | disclosed |