Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088409 | 0.84 | GAA (0.52) | GAATDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL2371884 | 0.79 | GAA (0.48) | GAATDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7626993 | 0.78 | GAA (0.37) | GAATDP1CYP1A2LMNANFKB1 | |
| SCHEMBL374336 | 0.76 | — | — | |
| SCHEMBL12356605 | 0.75 | GAA (0.39) | GAATDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11444075 | 0.75 | RAB9A (0.49) | GAATDP1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9818452 | 0.75 | KCNH3 (0.41) | GAATDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8612319 | 0.75 | MAPK1 (0.39) | GAATDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL30273056 | 0.75 | GAA (0.39) | GAATDP1ALDH1A1KMT2AMEN1 | |
| Propazine SCHEMBL67521 | 0.75 | GAA (1.00) | GAATDP1POLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003374-A1 | Process for the preparation of a substituted triazine | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-08-08 | — | — | EP | disclosed |