Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479657 | 0.85 | CCR2 (0.46) | CCR2HSD11B1PTGS2MAOBMAOA | |
| SCHEMBL11486398 | 0.85 | KDM4E (0.35) | CCR2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL11487632 | 0.79 | CYP2D6 (0.49) | CCR2HSD11B1CYP2D6MEN1KMT2A | |
| SCHEMBL4944760 | 0.77 | CYP2D6 (0.47) | CCR2HSD11B1CYP2D6MEN1KMT2A | |
| SCHEMBL3744181 | 0.75 | HSD11B1 (0.44) | CCR2HSD11B1PTGS2MAOBMAOA | |
| SCHEMBL27952891 | 0.75 | HSD11B1 (0.44) | CCR2HSD11B1PTGS2MAOBMAOA | |
| SCHEMBL5791908 | 0.75 | HSD11B1 (0.44) | CCR2HSD11B1PTGS2MAOBMAOA | |
| SCHEMBL11493927 | 0.74 | CCR2 (0.51) | CCR2HSD11B1PTGS2MAOBMAOA | |
| SCHEMBL11487589 | 0.71 | HSD11B1 (0.56) | CCR2HSD11B1PTGS2HTTATM | |
| SCHEMBL1581700 | 0.71 | HSD11B1 (0.42) | CCR2HSD11B1CYP2D6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001566-A2 | Cyclobutanecarboxylic acid derivatives, processes for their preparation and their use as insecticides | BAYER AG (DE) | 1979-05-02 | — | — | EP | disclosed |