Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030606 | 0.71 | HSD11B1 (1.00) | HSD11B1MEN1KMT2A | |
| SCHEMBL11568427 | 0.71 | CCR2 (0.47) | HSD11B1CCR2MEN1KMT2APTGS2 | |
| SCHEMBL11493927 | 0.69 | CCR2 (0.51) | HSD11B1CCR2MEN1KMT2APTGS2 | |
| SCHEMBL11487632 | 0.68 | CYP2D6 (0.49) | HSD11B1CCR2MEN1KMT2AAPP | |
| SCHEMBL17761265 | 0.67 | CYP3A4 (0.48) | HSD11B1CCR2MEN1KMT2AAPP | |
| SCHEMBL25502573 | 0.66 | MAOB (0.43) | HSD11B1CCR2HTTATM | |
| SCHEMBL14300090 | 0.66 | HSD11B1 (0.70) | HSD11B1MEN1KMT2AHTT | |
| SCHEMBL4944760 | 0.66 | CYP2D6 (0.47) | HSD11B1CCR2MEN1KMT2AAPP | |
| SCHEMBL20540105 | 0.65 | HSD11B1 (0.47) | HSD11B1MEN1KMT2APTGS2 | |
| Acetic Acid SCHEMBL27477631 | 0.65 | CES2 (0.55) | HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001566-B1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0001566-A2 | Cyclobutanecarboxylic acid derivatives, processes for their preparation and their use as insecticides | BAYER AG (DE) | 1979-05-02 | — | — | EP | disclosed |