Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565738 | 0.78 | MEN1 (0.38) | CYP2D6RAB9AALDH1A1HSD17B10MEN1 | |
| SCHEMBL11566990 | 0.78 | POLB (0.42) | CYP2D6RAB9AALDH1A1HSD17B10POLB | |
| SCHEMBL28356863 | 0.69 | MAOA (0.32) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL27970167 | 0.67 | GAA (0.50) | RAB9AALDH1A1HSD17B10POLBGAA | |
| SCHEMBL10038039 | 0.64 | RAB9A (0.76) | RAB9AALDH1A1HSD17B10POLBGAA | |
| SCHEMBL27696136 | 0.64 | EGFR (0.35) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL15906510 | 0.62 | CYP2D6 (0.47) | CYP2D6ALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL27701173 | 0.61 | RAB9A (0.33) | RAB9AMEN1KMT2AATM | |
| SCHEMBL3994733 | 0.61 | CYP2D6 (0.55) | CYP2D6POLBMEN1KMT2AATM | |
| SCHEMBL28069840 | 0.60 | CYP2D6 (0.50) | CYP2D6ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144258-A | ORGANIC PIGMENTS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4065481-A | 1:1-Azomethine-metal-complex dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-3988323-A | PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3974149-A | TONERS | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |