SCHEMBL1156860

SCHEMBL1156860

CC(C)(c1ccccc1)c1ccccc1-c1ccccc1OC(=O)Oc1ccccc1-c1ccccc1C(C)(C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 3/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 3/20 0.37
ESR1 P03372 1/20 0.37
CYP3A4 P08684 1/20 0.37
ESR2 Q92731 1/20 0.37
BCHE P06276 1/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
KCNN4 O15554 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
ELANE P08246 2/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1156866 0.91 TDP1 (0.40) ATMTDP1KDM4EALDH1A1ESR1
SCHEMBL1157233 0.88 ATM (0.37) ATMTDP1KDM4EHPGDHSD17B10
SCHEMBL1673995 0.87 TDP1 (0.47) ATMTDP1KDM4EHPGDHSD17B10
SCHEMBL1157159 0.84 HPGD (0.40) ATMTDP1KDM4EHPGDHSD17B10
SCHEMBL1157030 0.83 TDP1 (0.47) ATMTDP1KDM4EHPGDHSD17B10
SCHEMBL247688 0.81 ATM (0.43) ATMTDP1KDM4EHPGDHSD17B10
SCHEMBL247099 0.81 TDP1 (0.40) ATMTDP1KDM4EHPGDHSD17B10
SCHEMBL235936 0.81 ALDH1A1 (0.44) TDP1KDM4EHPGDHSD17B10ALDH1A1
SCHEMBL1157238 0.80 TDP1 (0.37) ATMTDP1KDM4EHSD17B10ALDH1A1
SCHEMBL5706116 0.79 SLC6A3 (0.55) ATMKDM4EHPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
CN-109153776-B Copolycarbonate as support material in 3D printing 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
US-20120231278-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-13 US disclosed
US-8044122-B2 Polycarbonate composition containing UV absorber BAYER MATERIALSCIENCE AG (DE) 2011-10-25 US disclosed
US-7879967-B2 End groups containing alkylsiloxane substituted phenol compounds ; extrusion; molding materials BAYER MATERIALSCIENCE AG (DE) 2011-02-01 US disclosed
US-20090258978-A1 POLYCARBONATE COMPOSITION CONTAINING UV ABSORBER BAYER MATERIALSCIENCE AG (DE) 2009-10-15 US disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
US-20080249234-A1 Modified Polycarbonates, Polyester Carbonates and Polyesters Having Improved Elongation Behaviour and Flame Resistance BAYER MATERIALSCIENCE AG (DE) 2008-10-09 US disclosed
US-6596840-B1 By reacting diphenol, carbonic acid dieseter and alkylphenol chain terminator using phosphonium salt catalyst; ester interchange BAYER AKTIENGESELLSCHAFT (DE) 2003-07-22 US disclosed
US-20030105272-A1 Production and use of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-06-05 US disclosed
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed
EP-0434998-B1 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof G E PLASTICS JAPAN LTD (JP) 1996-02-07 EP disclosed
US-5459225-A Ester interchange in antioxidant presence IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-10-17 US disclosed
US-5349042-A Ester interchange and dechlorination with carbonation IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed
EP-0561363-A2 Process for producing polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-22 EP disclosed
US-5187242-A Workable molding materials containing aliphatic carboxylic acids and aromatic diols as monomers, impact strenth, transparency GENERAL ELECTRIC COMPANY (US) 1993-02-16 US disclosed
EP-0434998-A2 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed