Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549339 | 0.88 | ALDH1A1 (0.39) | TSHRCYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL4154405 | 0.87 | TSHR (0.37) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11571137 | 0.85 | CA2 (0.39) | TSHRALDH1A1PTPN5TDP1 | |
| SCHEMBL11569511 | 0.83 | ALDH1A1 (0.42) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15741151 | 0.81 | NPC1 (0.35) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11301324 | 0.81 | PDK2 (0.37) | TSHRCYP2C9CYP2C19ALDH1A1TDP1 | |
| SCHEMBL11294608 | 0.80 | CYP1A2 (0.33) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2680009 | 0.78 | CYP1A2 (0.33) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11496194 | 0.77 | RAB9A (0.36) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4147317 | 0.76 | APEX1 (0.36) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004026-A1 | Hydrolytically stable ortho-alkylated phenyl phosphonites and stabilized compositions | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | disclosed |