Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563867 | 0.85 | KCNA3 (0.41) | ALDH1A1KDM4EHSD17B10OPRM1OPRD1 | |
| SCHEMBL11566234 | 0.85 | OPRM1 (0.45) | ALDH1A1KDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL11564520 | 0.85 | KCNA3 (0.57) | ALDH1A1OPRM1OPRD1OPRK1KMT2A | |
| SCHEMBL11565335 | 0.83 | KCNA3 (0.52) | ALDH1A1OPRM1OPRD1OPRK1KMT2A | |
| SCHEMBL11562170 | 0.83 | MEN1 (0.51) | KDM4EOPRM1OPRD1OPRK1KMT2A | |
| SCHEMBL11793631 | 0.81 | OPRM1 (0.44) | ALDH1A1KDM4EOPRM1OPRD1OPRK1 | |
| SCHEMBL11563022 | 0.81 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10KMT2ATDP1 | |
| SCHEMBL11563023 | 0.80 | KCNA3 (0.47) | ALDH1A1OPRM1OPRD1OPRK1MAPT | |
| SCHEMBL11565124 | 0.80 | KDM4E (0.51) | ALDH1A1KDM4EHSD17B10OPRM1OPRD1 | |
| SCHEMBL11564832 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |