Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 4/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574238 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL3453702 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL11570132 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL11240874 | 0.81 | ADRA1D (0.60) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL11570772 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL7794600 | 0.78 | ADRA1A (0.64) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL7797849 | 0.77 | ADRA1A (0.63) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL11754127 | 0.77 | KDM4E (0.74) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL7794602 | 0.77 | KDM4E (0.74) | KDM4EALDH1A1HPGDGLAADRA1D | |
| SCHEMBL7787706 | 0.76 | KDM4E (0.73) | KDM4EALDH1A1HPGDGLAADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004389-A2 | 4-Amino-6,7-dimethoxy quinazoline derivatives, process for their preparation, their use and a pharmaceutical composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-10-03 | — | — | EP | disclosed |