Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | CTSB | P07858 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562969 | 0.96 | CTSL (0.36) | MEN1POLBKMT2ACTSSCTSK | |
| SCHEMBL8040888 | 0.75 | CTSL (0.41) | MEN1POLBKMT2ACTSSCTSK | |
| SCHEMBL26880884 | 0.74 | CTSL (0.38) | CTSSCTSKCTSBCTSLRXFP1 | |
| SCHEMBL1586413 | 0.74 | CTSL (0.53) | MEN1KMT2ACTSSCTSKCTSB | |
| SCHEMBL23795558 | 0.73 | CTSB (0.42) | MEN1POLBKMT2ACTSSCTSK | |
| SCHEMBL3831093 | 0.72 | CTSL (0.45) | MEN1POLBKMT2ACTSSCTSK | |
| SCHEMBL10107201 | 0.72 | ALDH1A1 (0.39) | MEN1POLBKMT2AKDM4EATM | |
| SCHEMBL22455228 | 0.71 | CTSC (0.41) | CTSSCTSKCTSBCTSL | |
| SCHEMBL16372238 | 0.71 | CTSC (0.38) | MEN1POLBKMT2ACTSSCTSK | |
| SCHEMBL24848504 | 0.70 | CTSL (0.43) | CTSSCTSKCTSBCTSLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156738-A | Ureidonitriles useful as antihypertensives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-05-29 | — | — | US | disclosed |