SCHEMBL1156901

SCHEMBL1156901

CCCCCCc1csc2ccsc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.51
LIPG Q9Y5X9 1/20 0.39
TYR P14679 2/20 0.38
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYSLTR2 Q9NS75 2/20 0.35
CYSLTR1 Q9Y271 2/20 0.35
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27808058 1.00 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL25229247 1.00 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL11021583 1.00 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL28041682 1.00 GPR35 (0.51) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1157073 0.84 GPR35 (0.50) GPR35LIPGTYRTP53CYP3A4
SCHEMBL12732792 0.82 GPR35 (0.48) GPR35LIPGTYRTP53CYP3A4
SCHEMBL16758705 0.82 GPR35 (0.42) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1413219 0.79 GPR35 (0.53) GPR35LIPGTYRTP53CYP3A4
SCHEMBL2280270 0.79 GPR35 (0.53) GPR35LIPGTYRTP53CYP3A4
SCHEMBL1156794 0.79 GPR35 (0.53) GPR35LIPGTYRTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101580567-B Conjugated polymer containing thieno[3,2-b] thiophene ethylene on fundamental chain as well as preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2011-08-10 CN claimed
CN-101580567-A Conjugated polymer containing thieno[3,2-b] thiophene ethylene on fundamental chain as well as preparation method and application thereof CHINESE ACAD INST CHEMISTRY (CN) 2009-11-18 CN claimed
CN-113185539-A Ternary ring benzothiadiazole organic small molecular material, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-07-30 CN disclosed
US-10815256-B2 Dithiophene compound, preparation and its application in organic photovoltaics thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-10-27 US disclosed
US-20190300554-A1 NOVEL DITHIOPHENE COMPOUND, PREPARATION AND ITS APPLICATION IN ORGANIC PHOTOVOLTAICS THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2019-10-03 US disclosed
EP-2308882-B1 Fused thiophenes and uses thereof CORNING INC (US) 2018-06-13 EP disclosed
EP-2773646-B1 CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2016-06-15 EP disclosed
WO-2016003097-A1 ORGANIC SEMICONDUCTOR COMPOUND, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTRONIC ELEMENT AND ORGANIC SOLAR CELL ELEMENT COMPRISING SAME 부산대학교 산학협력단 2016-01-07 WO disclosed
EP-2129678-B1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2015-05-27 EP disclosed
US-8846855-B2 Conjugated fused thiophenes, methods of making conjugated fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2014-09-30 US disclosed
EP-1799688-B1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF CORNING INC (US) 2013-06-19 EP disclosed
US-20110082278-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2011-04-07 US disclosed
US-7893191-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2011-02-22 US disclosed
US-20110040042-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2011-02-17 US disclosed
US-7838623-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2010-11-23 US disclosed
US-7705108-B2 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED (US) 2010-04-27 US disclosed
US-20100010237-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF HE MINGQIAN 2010-01-14 US disclosed
CN-101580567-A Conjugated polymer containing thieno[3,2-b] thiophene ethylene on fundamental chain as well as preparation method and application thereof CHINESE ACAD INST CHEMISTRY (CN) 2009-11-18 CN disclosed
US-20070265418-A1 Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof CORNING INCORPORATED 2007-11-15 US disclosed
US-20070161776-A1 Fused thiophenes, methods for making fused thiophenes, and uses thereof CORNING INCORPORATED 2007-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110040042-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4429/4885LIPG 4076/4885TYR 91/4885
US-20190300554-A1 NOVEL DITHIOPHENE COMPOUND, PREPARATION AND ITS APPLICATION IN ORGANIC PHOTOVOLTAICS THEREOF DDT, TST, DIMT1 GPR35 1934/4885LIPG 4277/4885TYR 61/4885
US-20110082278-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4429/4885LIPG 4076/4885TYR 91/4885
US-10815256-B2 Dithiophene compound, preparation and its application in organic photovoltaics thereof DDT, TST, DIMT1 GPR35 1950/4885LIPG 4306/4885TYR 136/4885
US-20100010237-A1 FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF TPMT, TST, TYMP GPR35 4520/4885LIPG 3969/4885TYR 93/4885
US-20070265418-A1 Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof TPMT, TST, TYMP GPR35 4429/4885LIPG 4076/4885TYR 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.