Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12732792 | 0.97 | GPR35 (0.48) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL25229247 | 0.84 | GPR35 (0.51) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL11021583 | 0.84 | GPR35 (0.51) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL27808058 | 0.84 | GPR35 (0.51) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL1156901 | 0.84 | GPR35 (0.51) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL28041682 | 0.84 | GPR35 (0.51) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL1156982 | 0.84 | GPR35 (0.53) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL9948836 | 0.84 | GPR35 (0.53) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL1156975 | 0.84 | GPR35 (0.53) | GPR35LIPGTYRTP53CYP3A4 | |
| SCHEMBL1363005 | 0.82 | GPR35 (0.51) | GPR35LIPGTYRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308882-B1 | Fused thiophenes and uses thereof | CORNING INC (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-2773646-B1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2773646-B1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2129678-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2015-05-27 | — | — | EP | disclosed |
| EP-2129678-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8846855-B2 | Conjugated fused thiophenes, methods of making conjugated fused thiophenes, and uses thereof | CORNING INCORPORATED (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2773646-A1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | Corning Incorporated (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2773687-A1 | FUSED THIOPHENES, METHODS OF MAKING FUSED THIOPHENES, AND USES THEREOF | Corning Inc. (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-1799688-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-1799688-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2013-06-19 | — | — | EP | disclosed |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | HE MINGQIAN | 2010-01-14 | — | — | US | disclosed |
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | HE MINGQIAN | 2010-01-14 | — | — | US | disclosed |
| EP-2129678-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008106019-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2008-09-04 | — | — | WO | disclosed |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | CORNING INCORPORATED | 2007-11-15 | — | — | US | disclosed |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | CORNING INCORPORATED | 2007-11-15 | — | — | US | disclosed |
| US-20070161776-A1 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| US-20070161776-A1 | Fused thiophenes, methods for making fused thiophenes, and uses thereof | CORNING INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| EP-1799688-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC. (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006031893-A2 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INCORPORATED (US) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010237-A1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | TPMT, TST, TYMP | GPR35 4520/4885LIPG 3969/4885TYR 93/4885 |
| US-20070265418-A1 | Fused Thiophenes, Methods for Making Fused Thiophenes, and Uses Thereof | TPMT, TST, TYMP | GPR35 4429/4885LIPG 4076/4885TYR 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.