Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.47 |
| ▸ | ATP4B | P51164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466217 | 0.84 | KDM4E (0.86) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL2226546 | 0.80 | ALDH1A1 (0.56) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL2222461 | 0.80 | GFER (0.66) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL7534286 | 0.80 | KDM4E (0.69) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL7676006 | 0.80 | KDM4E (0.69) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL4281217 | 0.78 | RAB9A (0.75) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL11455457 | 0.78 | RAB9A (0.75) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL4283884 | 0.78 | KDM4E (1.00) | KDM4ERAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL23578319 | 0.77 | MAOB (0.47) | LMNANPC1MEN1KMT2AMAPT | |
| Methane SCHEMBL4574569 | 0.77 | IDO1 (0.44) | KDM4ESMN1; SMN2LMNANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54066674-A | — | — | None | — | — | JP | disclosed |
| JP-S5466674-A | NOVEL PHENYLACETIC ACID DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1979-05-29 | — | — | JP | disclosed |