Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 11/20 | 0.49 |
| ▸ | GAA | P10253 | 11/20 | 0.49 |
| ▸ | SI | P14410 | 11/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 11/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479170 | 0.82 | MEN1 (0.43) | GAACBFBKCNMA1CYP1A2CYP3A4 | |
| SCHEMBL7477741 | 0.77 | PKN1 (0.54) | MGAMGAASIMGAM2 | |
| SCHEMBL4107024 | 0.75 | BCHE (0.49) | AURKACBFBALKBH3CYP3A4HSD17B10 | |
| SCHEMBL7016670 | 0.73 | MEN1 (0.39) | CBFBKCNMA1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15084733 | 0.71 | NPC1 (0.39) | AURKACBFBALKBH3CYP1A2CYP2C19 | |
| SCHEMBL7649005 | 0.70 | CYP3A4 (0.50) | GAACYP1A2CYP3A4CYP2D6ALOX15 | |
| SCHEMBL11198421 | 0.69 | HRH4 (0.58) | AURKAMGAMGAASIMGAM2 | |
| SCHEMBL7600366 | 0.69 | HTR3A (0.59) | AURKAMGAMGAASIMGAM2 | |
| SCHEMBL28790670 | 0.69 | BCHE (0.42) | AURKACBFBALKBH3CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL28521741 | 0.69 | CYP3A4 (0.48) | GAACYP1A2CYP3A4CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |