Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337129 | 0.97 | MEN1 (0.40) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11346998 | 0.91 | KDM4E (0.34) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11572457 | 0.89 | TSHR (0.41) | ALDH1A1SMN1; SMN2TRPM8TSHRSIGMAR1 | |
| SCHEMBL11572452 | 0.87 | LTB4R2 (0.34) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11347000 | 0.86 | SIGMAR1 (0.41) | ALDH1A1TRPM8TSHRSIGMAR1 | |
| SCHEMBL11465401 | 0.86 | ALDH1A1 (0.43) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11595372 | 0.83 | SLC18A3 (0.50) | MEN1KMT2ASIGMAR1OPRM1OPRD1 | |
| SCHEMBL11350705 | 0.82 | ALDH1A1 (0.45) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11437590 | 0.81 | MEN1 (0.43) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL11334204 | 0.81 | SLC18A3 (0.52) | MEN1KMT2ASIGMAR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |