Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334204 | 0.97 | SLC18A3 (0.52) | SLC18A3OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11465401 | 0.85 | ALDH1A1 (0.43) | OPRM1OPRK1OPRD1SIGMAR1CHRM3 | |
| SCHEMBL11569488 | 0.83 | KDM4E (0.38) | OPRM1OPRK1OPRD1SIGMAR1CHRM3 | |
| SCHEMBL11571013 | 0.82 | SLC18A3 (0.44) | SLC18A3OPRM1SIGMAR1CHRM3CHRM2 | |
| SCHEMBL11350705 | 0.82 | ALDH1A1 (0.45) | OPRM1SIGMAR1CHRM3CHRM2MEN1 | |
| SCHEMBL11330424 | 0.81 | SLC18A3 (0.43) | SLC18A3OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11456844 | 0.81 | SLC18A3 (0.48) | SLC18A3OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11337129 | 0.80 | MEN1 (0.40) | SLC18A3OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11437590 | 0.80 | MEN1 (0.43) | SLC18A3OPRM1OPRK1OPRD1CHRM3 | |
| SCHEMBL11332124 | 0.80 | SLC18A3 (0.47) | SLC18A3OPRM1OPRK1OPRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |