Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346418 | 0.91 | ALDH1A1 (0.35) | HTR1ALTB4R2CHRM2CHRM3MEN1 | |
| SCHEMBL11568723 | 0.87 | KMT2A (0.36) | HTR1ACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL11570684 | 0.87 | KMT2A (0.36) | HTR1ACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL11595050 | 0.83 | KDM4E (0.43) | CHRM2CHRM3MEN1KMT2AKDM4E | |
| SCHEMBL11341461 | 0.78 | KMT2A (0.40) | HTR1ACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL11339668 | 0.78 | KMT2A (0.40) | HTR1ACHRM2CHRM3MEN1KMT2A | |
| SCHEMBL11569547 | 0.78 | PYGL (0.34) | HTR1AMEN1KMT2ACYP1A2 | |
| SCHEMBL11346436 | 0.77 | TACR2 (0.35) | HTR1AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11334003 | 0.75 | KDM4E (0.44) | CHRM2CHRM3MEN1KMT2AKDM4E | |
| SCHEMBL11456609 | 0.74 | ALDH1A1 (0.39) | CHRM2CHRM3MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |