Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568723 | 1.00 | KMT2A (0.36) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11341461 | 0.91 | KMT2A (0.40) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11339668 | 0.91 | KMT2A (0.40) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11569546 | 0.87 | HTR1A (0.35) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11456609 | 0.85 | ALDH1A1 (0.39) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11447348 | 0.84 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11446728 | 0.84 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11571084 | 0.84 | CHRM2 (0.40) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11516820 | 0.83 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1MITFNPC1 | |
| SCHEMBL11518232 | 0.81 | KDM4E (0.38) | KMT2AALDH1A1MEN1MITFNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |