Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569649 | 1.00 | KMT2A (0.50) | KMT2AMEN1LMNASMN1; SMN2POLB | |
| SCHEMBL11721586 | 0.87 | LMNA (0.46) | KMT2AMEN1LMNASMN1; SMN2POLB | |
| SCHEMBL11721599 | 0.87 | LMNA (0.46) | KMT2AMEN1LMNASMN1; SMN2POLB | |
| SCHEMBL6955855 | 0.80 | LMNA (0.53) | KMT2AMEN1LMNAPOLBALDH1A1 | |
| SCHEMBL3355917 | 0.78 | SMN1; SMN2 (0.50) | KMT2AMEN1LMNASMN1; SMN2POLB | |
| SCHEMBL3355913 | 0.78 | SMN1; SMN2 (0.50) | KMT2AMEN1LMNASMN1; SMN2POLB | |
| SCHEMBL9568018 | 0.76 | LMNA (0.58) | KMT2AMEN1LMNAPOLBALDH1A1 | |
| SCHEMBL8862391 | 0.76 | MGLL (0.48) | LMNAPOLBALDH1A1 | |
| SCHEMBL9848728 | 0.76 | MGLL (0.48) | LMNAPOLBALDH1A1 | |
| SCHEMBL8416322 | 0.76 | LMNA (0.62) | LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161580-A | Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4089845-A | Thermosetting mixtures which are stable on storage from polyimide and .beta. | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |