Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8862391 | 0.95 | MGLL (0.48) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL9848728 | 0.95 | MGLL (0.48) | LMNAPOLBALDH1A1MGLL | |
| SCHEMBL9568018 | 0.81 | LMNA (0.58) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL8416322 | 0.80 | LMNA (0.62) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL8419580 | 0.80 | LMNA (0.62) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL8416318 | 0.80 | LMNA (0.62) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL11569645 | 0.80 | KMT2A (0.50) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL11569649 | 0.80 | KMT2A (0.50) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL154822 | 0.79 | LMNA (0.44) | LMNAPOLBALDH1A1MGLLNPSR1 | |
| SCHEMBL10290385 | 0.79 | LMNA (0.64) | LMNAPOLBALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6482841-B1 | Pyridyl compounds and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2002-11-19 | — | — | US | disclosed |
| EP-1023267-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019302-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 1999-04-22 | — | — | WO | disclosed |