Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812586 | 0.78 | MAPT (0.52) | MEN1KMT2ADDB1CRBNMAPT | |
| SCHEMBL11090245 | 0.75 | CRBN (0.39) | MEN1KMT2ADDB1CRBNMAPT | |
| SCHEMBL28539505 | 0.75 | ALDH1A1 (0.38) | CRBNMAPTALDH1A1HSD17B10NPC1 | |
| SCHEMBL7337733 | 0.75 | CRBN (0.39) | MEN1KMT2ADDB1CRBNMAPT | |
| SCHEMBL31599173 | 0.73 | ALDH1A1 (0.39) | MAPTALDH1A1HSD17B10USP2 | |
| SCHEMBL5796177 | 0.71 | POLB (0.55) | MEN1KMT2ADDB1CRBNMAPT | |
| SCHEMBL28894449 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2ADDB1CRBNMAPT | |
| SCHEMBL28536947 | 0.71 | DDB1 (0.43) | MEN1KMT2ADDB1CRBNALDH1A1 | |
| SCHEMBL28544519 | 0.69 | PARL (0.51) | MEN1KMT2ACRBNMAPTALDH1A1 | |
| SCHEMBL11266599 | 0.67 | BCHE (0.58) | MEN1KMT2ABCHEALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005914-A1 | Chemical process for the preparation of beta-lactamase inhibitors, and so obtained compounds | BEECHAM GROUP PLC (GB) | 1979-12-12 | — | — | EP | disclosed |