Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902085 | 0.91 | CISD1 (0.50) | CISD1TDP1ALDH1A1POLBHTT | |
| SCHEMBL12316423 | 0.87 | TDP1 (0.45) | TDP1ALDH1A1LMNAPOLBHTT | |
| SCHEMBL405745 | 0.85 | TDP1 (0.45) | CISD1TDP1ALDH1A1POLBHTT | |
| SCHEMBL27644086 | 0.82 | TDP1 (0.59) | PPARGPPARATDP1ALDH1A1LMNA | |
| SCHEMBL6439858 | 0.80 | HTR4 (0.60) | ALDH1A1MEN1KMT2AHTR4 | |
| SCHEMBL5754001 | 0.80 | TDP1 (0.47) | TDP1ALDH1A1LMNAPOLBHTT | |
| SCHEMBL7529723 | 0.80 | HTT (0.59) | CISD1PPARGALDH1A1LMNATSHR | |
| SCHEMBL12316387 | 0.79 | HTT (0.55) | PPARGTDP1ALDH1A1LMNATSHR | |
| SCHEMBL8902203 | 0.78 | TDP1 (0.47) | TDP1ALDH1A1LMNANPSR1POLB | |
| SCHEMBL12316393 | 0.77 | METAP2 (0.44) | CISD1TDP1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138492-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | ANPHAR, S.A. (ES) | 1979-02-06 | — | — | US | disclosed |