Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.96 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.96 |
| ▸ | MEN1 | O00255 | 1/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.96 |
| ▸ | MAPT | P10636 | 1/20 | 0.96 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.96 |
| ▸ | PPARG | P37231 | 5/20 | 0.81 |
| ▸ | FABP2 | P12104 | 2/20 | 0.81 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 3/20 | 0.59 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.59 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.59 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.59 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clofibric Acid SCHEMBL102826 | 0.98 | PPARA (1.00) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL2227936 | 0.98 | PPARA (1.00) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL10634899 | 0.96 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL28722594 | 0.96 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL11798397 | 0.96 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL11798234 | 0.96 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL28571877 | 0.96 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL11798560 | 0.94 | PPARA (0.93) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL6350219 | 0.93 | PPARA (0.89) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| SCHEMBL9320807 | 0.93 | PPARA (0.89) | PPARACYP1A2CYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993741-B1 | INLINE APPLICATION OF COATINGS | COOK MEDICAL TECHNOLOGIES LLC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-8523937-B2 | Controlled drug delivery using a zein layer modified with levulinic acid | COOK MEDICAL TECHNOLOGIES LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8303648-B2 | Artificial venous valve containing therapeutic agent | COOK MEDICAL TECHNOLOGIES LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-8092819-B2 | Implantable medical device coated with a bioactive agent | Cook Medical Technologies LLC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8024851-B2 | Method of producing a radially expandable prosthesis | COOK MEDICAL TECHNOLOGIES LLC (US) | 2011-09-27 | — | — | US | disclosed |
| US-7914841-B2 | Inline application of coatings | COOK MEDICAL TECHNOLOGIES LLC (US) | 2011-03-29 | — | — | US | disclosed |
| EP-1981560-B1 | ZEIN COATED MEDICAL DEVICE | MED INST INC (US) | 2010-09-08 | — | — | EP | disclosed |
| US-20090258050-A1 | Controlled Drug Delivery Using a Zein Layer Modified with Levulinic Acid | MED INSTITUTE, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| EP-1993626-A2 | IMPLANTABLE MEDICAL DEVICE COATED WITH BIOACTIVE AGENT | Med Institute, Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| US-20080178459-A1 | METHOD OF PRODUCING A RADIALLY EXPANDABLE PROSTHESIS | COOK INCORPORATED (US) | 2008-07-31 | — | — | US | disclosed |
| US-20070299518-A1 | Device with nanocomposite coating for controlled drug release | MED INSTITUTE, INC. (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070265699-A1 | Artificial venous valve containing therapeutic agent | MED INSTITUTE, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070207184-A1 | Implantable medical device coated with a bioactive agent | MED INSTITUTE, INC (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070207183-A1 | Zein coated medical device | MED INSTITUTE, INC. (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070196423-A1 | Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent | MED INSTITUTE, INC. (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2007089592-A2 | IMPLANTABLE MEDICAL DEVICE COATED WITH BIOACTIVE AGENT | MED INSTITUTE, INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070182055-A1 | Inline application of coatings | COOK INCORPORATED (US) | 2007-08-09 | — | — | US | disclosed |
| US-20070043423-A1 | Intraluminal device with a hollow structure | MED INSTITUTE INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-4058390-A | Amine salts of phenyl-4-hydroxypyridazines and the preparation and herbicidal compositions thereof | CHEMIE LINZ AKTIENGESELLSCHAFT (OE) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258050-A1 | Controlled Drug Delivery Using a Zein Layer Modified with Levulinic Acid | LTN1, LOXL2, LOXL1 | PPARA 1419/4885CYP1A2 3719/4885CYP3A4 3862/4885 |
| US-20070207183-A1 | Zein coated medical device | PCSK9, ZYX, ZFX | PPARA 2783/4885CYP1A2 4386/4885CYP3A4 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.