Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 4/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890174 | 0.91 | KDM4E (0.57) | KDM4EMCL1KMT2AHPGDTDP1 | |
| SCHEMBL2300012 | 0.85 | KDM4E (0.47) | KDM4EMCL1KMT2AHPGDTDP1 | |
| SCHEMBL11570117 | 0.85 | MAPT (0.47) | KDM4EKMT2AHPGDTDP1MAPT | |
| SCHEMBL2059355 | 0.84 | CSNK2A2 (0.49) | KDM4EMCL1KMT2AHPGDMAPT | |
| SCHEMBL2058911 | 0.82 | THRA (0.47) | KDM4EMCL1KMT2AHPGDPKM | |
| SCHEMBL15517469 | 0.81 | LMNA (0.53) | KDM4EKMT2AHPGDMAPTTSHR | |
| SCHEMBL3201351 | 0.81 | KMT2A (0.55) | KDM4EMCL1KMT2AHPGDTSHR | |
| SCHEMBL8240454 | 0.81 | MCL1 (0.45) | KDM4EMCL1KMT2AHPGDPKM | |
| SCHEMBL2059557 | 0.81 | AGBL2 (0.46) | KDM4EMCL1KMT2AHPGDPKM | |
| SCHEMBL14931907 | 0.81 | MCL1 (0.45) | KDM4EMCL1KMT2AHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |