SCHEMBL11570628

SCHEMBL11570628

CC(=O)OC(C)c1c(C)cccc1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.38
CYP3A4 P08684 3/20 0.38
TSHR P16473 2/20 0.38
PIK3CA P42336 1/20 0.38
ALDH1A1 P00352 8/20 0.36
HSD17B10 Q99714 3/20 0.36
CFTR P13569 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.35
ESR1 P03372 1/20 0.34
KCNH2 Q12809 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10430940 0.81 MMP2 (0.46) TSHRALDH1A1HSD17B10CFTRKDM4E
SCHEMBL28133620 0.77 CD44 (0.42) CD44CYP3A4TSHRPIK3CAALDH1A1
SCHEMBL13979941 0.77 POLB (0.43) TSHRALDH1A1KDM4EHPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL27502509 0.77 CYP3A4 (0.42) CYP3A4TSHRPIK3CAALDH1A1HSD17B10
SCHEMBL27670774 0.75 CD44 (0.43) CD44CYP3A4TSHRPIK3CAALDH1A1
SCHEMBL9292030 0.74 ALDH1A1 (0.42) CYP3A4TSHRALDH1A1HSD17B10CA12
SCHEMBL6975031 0.74 ALDH1A1 (0.39) CYP3A4TSHRALDH1A1HSD17B10CFTR
SCHEMBL10588711 0.74 CD44 (0.42) CD44CYP3A4TSHRPIK3CAALDH1A1
SCHEMBL341157 0.74 ALDH1A1 (0.39) CYP3A4TSHRALDH1A1HSD17B10CFTR
SCHEMBL111214 0.72 ADRA2A (0.38) CYP3A4TSHRALDH1A1HSD17B10CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003656-A2 Process for the diazotisation of amines IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-08-22 EP disclosed