Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16775636 | 0.98 | SIGMAR1 (0.47) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL14966049 | 0.84 | CYP3A4 (0.43) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL28981632 | 0.83 | SIGMAR1 (0.48) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL2486157 | 0.79 | CYP3A4 (0.39) | SIGMAR1SLC6A2SLC6A4HPGDALDH1A1 | |
| SCHEMBL20091630 | 0.77 | CYP3A4 (0.40) | SIGMAR1SLC6A2SLC6A4HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL28024977 | 0.77 | CYP3A4 (0.38) | SIGMAR1HPGDALDH1A1TSHRSLC6A3 | |
| SCHEMBL20091551 | 0.74 | LMNA (0.48) | SIGMAR1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL11679532 | 0.72 | CYP3A4 (0.33) | SIGMAR1SLC6A2SLC6A4HPGDALDH1A1 | |
| SCHEMBL11661164 | 0.71 | CYP3A4 (0.35) | SIGMAR1SLC6A2SLC6A4HPGDALDH1A1 | |
| SCHEMBL28696191 | 0.69 | SIGMAR1 (0.53) | SIGMAR1ADRB1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110252411-B | Complex platinum catalyst for producing epoxy-terminated silicone oil and preparation method and application thereof | 江西蓝星星火有机硅有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-103917587-A | P-piperazine compounds as flame retardants | BASF SE | 2014-07-09 | — | — | CN | claimed |
| CN-110252411-B | Complex platinum catalyst for producing epoxy-terminated silicone oil and preparation method and application thereof | 江西蓝星星火有机硅有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-110252411-B | Complex platinum catalyst for producing epoxy-terminated silicone oil and preparation method and application thereof | 江西蓝星星火有机硅有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-103917587-A | P-piperazine compounds as flame retardants | BASF SE | 2014-07-09 | — | — | CN | disclosed |
| US-4145559-A | Esters of 4-substituted 2-methyleneglutaric acids and method for preparing same | ROHM AND HAAS COMPANY (US) | 1979-03-20 | — | — | US | disclosed |