SCHEMBL20091630

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2486157	0.98	CYP3A4 (0.39)	CYP3A4CYP2C9CYP2C19KCNH2CYP1A2
	Hydrochloric Acid SCHEMBL28024977	0.95	CYP3A4 (0.38)	CYP3A4CYP2C9CYP2C19KCNH2CYP1A2
	SCHEMBL11661164	0.92	CYP3A4 (0.35)	CYP3A4CYP2C9CYP2C19KCNH2CYP1A2
	SCHEMBL11679532	0.89	CYP3A4 (0.33)	CYP3A4CYP2C9CYP2C19KCNH2CYP1A2
	SCHEMBL14966049	0.87	CYP3A4 (0.43)	CYP3A4CYP2C9CYP2C19KCNH2CYP1A2
	SCHEMBL6901641	0.81	KCNH2 (0.41)	CYP3A4CYP2C9CYP2C19KCNH2CYP1A2
	SCHEMBL11679024	0.78	CYP3A4 (0.39)	CYP3A4CYP2C9CYP2C19KCNH2CYP1A2
	SCHEMBL20091551	0.77	LMNA (0.48)	CYP2C9CYP2C19TSHRSIGMAR1ALDH1A1
	SCHEMBL11570649	0.77	SIGMAR1 (0.48)	TSHRSIGMAR1HPGDALDH1A1SLC6A3
	SCHEMBL16775636	0.76	SIGMAR1 (0.47)	TSHRSIGMAR1HPGDALDH1A1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.