Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570829 | 1.00 | CTSS (0.56) | CTSSCTSKPSENENBACE1CTSD | |
| SCHEMBL8492297 | 0.95 | CTSS (0.61) | CTSSCTSKPSENENCTSDALDH1A1 | |
| SCHEMBL8492292 | 0.95 | CTSS (0.61) | CTSSCTSKPSENENCTSDALDH1A1 | |
| SCHEMBL31139338 | 0.93 | CTSS (0.64) | CTSSCTSKPSENENBACE1CTSD | |
| SCHEMBL31139352 | 0.93 | CTSS (0.64) | CTSSCTSKPSENENBACE1CTSD | |
| SCHEMBL4122350 | 0.91 | CTSS (0.64) | CTSSCTSKPSENENALDH1A1CA2 | |
| SCHEMBL4122354 | 0.91 | CTSS (0.64) | CTSSCTSKPSENENALDH1A1CA2 | |
| SCHEMBL22068618 | 0.89 | CTSS (0.65) | CTSSCTSKPSENENBACE1CTSD | |
| SCHEMBL22068619 | 0.89 | CTSS (0.65) | CTSSCTSKPSENENBACE1CTSD | |
| SCHEMBL11405307 | 0.89 | CTSS (0.68) | CTSSCTSKPSENENALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |