Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938726 | 0.80 | EPHX2 (0.42) | KDM4EEPHX2SIRT2SIRT1DDB1 | |
| SCHEMBL15973191 | 0.80 | KMT2A (0.58) | KDM4EEPHX2SIRT2SIRT1DDB1 | |
| SCHEMBL8633466 | 0.80 | CYP1A2 (0.50) | KDM4EEPHX2DDB1CRBNCYP2D6 | |
| SCHEMBL8128225 | 0.78 | DAO (0.48) | DAOCYP2D6CA12POLB | |
| SCHEMBL7696982 | 0.76 | EPHX2 (0.39) | KDM4EEPHX2DDB1CRBNCYP2D6 | |
| SCHEMBL9850086 | 0.75 | DDB1 (0.69) | EPHX2DDB1CRBNCYP2D6TSHR | |
| SCHEMBL1011633 | 0.75 | DDB1 (0.69) | EPHX2DDB1CRBNCYP2D6TSHR | |
| SCHEMBL9850110 | 0.74 | DDB1 (0.67) | EPHX2DDB1CRBNCYP2D6TSHR | |
| SCHEMBL28757730 | 0.72 | EPHX2 (0.47) | EPHX2DDB1CRBNDAOTSHR | |
| SCHEMBL23629780 | 0.71 | MPO (0.64) | MPOKDM4EFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104130247-B | Human T 2 R bitterness receptors and application thereof | 塞诺米克斯公司 | 2018-06-01 | — | — | CN | disclosed |
| US-4175206-A | Process for preparing a hydroxyphenylglycine compound | TANABE SEIYAKU CO., LTD. (JP) | 1979-11-20 | — | — | US | disclosed |