Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15973191 | 0.80 | KMT2A (0.58) | EPHX2DDB1CRBNMAPTMEN1 | |
| SCHEMBL8633466 | 0.76 | CYP1A2 (0.50) | EPHX2DDB1CRBNMAPTMEN1 | |
| SCHEMBL6938726 | 0.76 | EPHX2 (0.42) | EPHX2DDB1CRBNMAPTMEN1 | |
| SCHEMBL11570834 | 0.76 | MPO (0.49) | EPHX2DDB1CRBNALDH1A1KDM4E | |
| SCHEMBL8128225 | 0.74 | DAO (0.48) | MAPTPOLBCYP2D6 | |
| SCHEMBL9850086 | 0.72 | DDB1 (0.69) | EPHX2DDB1CRBNMEN1KMT2A | |
| SCHEMBL1011633 | 0.72 | DDB1 (0.69) | EPHX2DDB1CRBNMEN1KMT2A | |
| SCHEMBL9850110 | 0.70 | DDB1 (0.67) | EPHX2DDB1CRBNMEN1KMT2A | |
| SCHEMBL840750 | 0.70 | GABRA1 (0.64) | LMNAGABRA1GABRB2CYP2D6 | |
| SCHEMBL839300 | 0.69 | TOP2A (0.46) | EPHX2DDB1CRBNMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |