Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 4/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481476 | 0.83 | CTSS (0.35) | CTSSCTSK | |
| SCHEMBL11661955 | 0.76 | CTSS (0.38) | CTSSCTSK | |
| SCHEMBL28760575 | 0.76 | CTSS (0.38) | CTSSCTSK | |
| SCHEMBL11661957 | 0.76 | CTSS (0.38) | CTSSCTSK | |
| SCHEMBL11568492 | 0.73 | BACE1 (0.36) | PSENENRENBACE1 | |
| SCHEMBL7439978 | 0.73 | CTSS (0.52) | CTSSCTSKPSENENCTSD | |
| SCHEMBL15246059 | 0.72 | CTSS (0.41) | CTSSCTSKPSENEN | |
| SCHEMBL15246006 | 0.72 | CTSS (0.41) | CTSSCTSKPSENEN | |
| SCHEMBL22068617 | 0.72 | CTSS (0.41) | CTSSCTSKPSENEN | |
| SCHEMBL11567549 | 0.71 | ALDH1A1 (0.49) | CTSDENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |