Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545186 | 0.88 | GSTO1 (0.55) | GSTO1SMN1; SMN2CYP1A2TSHRCYP2C19 | |
| SCHEMBL5511176 | 0.87 | GSTO1 (0.51) | GSTO1SMN1; SMN2POLBHSD17B10KMT2A | |
| SCHEMBL11417368 | 0.86 | GSTO1 (0.50) | GSTO1POLBHSD17B10KMT2AKDM4E | |
| SCHEMBL11343142 | 0.86 | GSTO1 (0.53) | GSTO1SMN1; SMN2CYP1A2TSHRCYP2C19 | |
| SCHEMBL10962880 | 0.85 | GSTO1 (0.62) | GSTO1SMN1; SMN2CYP1A2TSHRCYP2C19 | |
| SCHEMBL11340154 | 0.85 | GSTO1 (0.49) | GSTO1SMN1; SMN2CYP1A2TSHRCYP2C19 | |
| SCHEMBL7967267 | 0.84 | GSTO1 (0.53) | GSTO1SMN1; SMN2CYP1A2TSHRCYP2C19 | |
| SCHEMBL11572034 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2TSHRCYP2C19KMT2A | |
| SCHEMBL11340163 | 0.82 | CA1 (0.58) | CA1CA2CA12CA6CA7 | |
| SCHEMBL11557173 | 0.80 | GSTO1 (0.55) | GSTO1SMN1; SMN2CYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001051-A2 | Derivatives of benzenesulfonamide, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-03-21 | — | — | EP | disclosed |