Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BDKRB2 | P30411 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570604 | 0.82 | CYP1A2 (0.44) | ALDH1A1CYP1A2CYP2D6APEX1PMP22 | |
| SCHEMBL16070582 | 0.81 | CYP1A2 (0.45) | CYP1A2CYP2D6APEX1PMP22SIGMAR1 | |
| SCHEMBL15736896 | 0.79 | BDKRB2 (0.52) | ALDH1A1BDKRB2ESR1ESR2 | |
| SCHEMBL11595912 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNABDKRB2FOLH1 | |
| SCHEMBL5635618 | 0.78 | LMNA (0.55) | ALDH1A1LMNAESR1ESR2 | |
| SCHEMBL11595916 | 0.77 | ALDH1A1 (0.45) | ALDH1A1LMNAFOLH1 | |
| SCHEMBL20164916 | 0.77 | CSNK1E (0.55) | ALDH1A1LMNA | |
| SCHEMBL111455 | 0.77 | CSNK1E (0.55) | ALDH1A1LMNA | |
| SCHEMBL10521595 | 0.76 | CSNK1E (0.58) | ALDH1A1LMNA | |
| SCHEMBL17027839 | 0.76 | CSNK1E (0.58) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175544-A | X-RAYS OF BODY FOR MEDICAL DIAGNOSIS | Lafayette Pharmacal Inc. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4022814-A | Iodine containing organic carbonates for use as radiographic agents | LAFAYETTE PHARMACAL, INC. (US) | 1977-05-10 | — | — | US | disclosed |