Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572373 | 0.89 | HPGD (0.43) | ALDH1A1SMN1; SMN2ADRA1ACPN1CPB2 | |
| SCHEMBL11420225 | 0.81 | ADRB3 (0.61) | ALDH1A1SMN1; SMN2POLBADRA2CADRA1A | |
| SCHEMBL8867745 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBKEAP1NR3C1 | |
| SCHEMBL8867750 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBKEAP1NR3C1 | |
| SCHEMBL11466281 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBKEAP1NR3C1 | |
| Hydrochloric Acid SCHEMBL9216889 | 0.79 | ADRB3 (0.59) | ALDH1A1SMN1; SMN2POLBADRA2CADRA1A | |
| Hydrochloric Acid SCHEMBL9216885 | 0.79 | ADRB3 (0.59) | ALDH1A1SMN1; SMN2POLBADRA2CADRA1A | |
| SCHEMBL6500176 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2POLBKEAP1NR3C1 | |
| SCHEMBL8132118 | 0.77 | ROCK2 (0.51) | ALDH1A1SMN1; SMN2POLBKEAP1 | |
| SCHEMBL11570666 | 0.76 | ADRA2C (0.52) | ALDH1A1SMN1; SMN2POLBADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179435-A | SULPHONIC ACID-FREE | CIBA-GEIGY CORPORATION (US) | 1979-12-18 | — | — | US | disclosed |
| US-4115381-A | FOR POLYESTER FIBERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |