Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319143 | 0.88 | KMT2A (0.69) | RARBMAPK1KMT2ACA1CA2 | |
| SCHEMBL11758882 | 0.87 | L3MBTL1 (0.50) | RARBMAPK1KMT2AGRIN2DGRIN2A | |
| SCHEMBL8084708 | 0.87 | KMT2A (0.59) | RARBMAPK1KMT2ATP53TSHR | |
| SCHEMBL8434202 | 0.87 | KMT2A (0.59) | RARBMAPK1KMT2ATP53TSHR | |
| SCHEMBL8436176 | 0.86 | TP53 (0.58) | RARBMAPK1KMT2ATP53TSHR | |
| SCHEMBL8072342 | 0.86 | TP53 (0.58) | RARBMAPK1KMT2ATP53TSHR | |
| SCHEMBL5091731 | 0.84 | TP53 (0.60) | RARBMAPK1KMT2ATP53TSHR | |
| SCHEMBL13953004 | 0.84 | TP53 (0.60) | RARBMAPK1KMT2ATP53TSHR | |
| SCHEMBL7613153 | 0.84 | RARB (0.69) | RARBMAPK1KMT2ATP53TSHR | |
| SCHEMBL4602775 | 0.84 | TP53 (0.60) | RARBMAPK1KMT2ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138579-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4051319-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-3957833-A | KILLING INSECTS, HORMONES | HOFFMANN-LA ROCHE INC. (US) | 1976-05-18 | — | — | US | disclosed |