Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977277 | 0.78 | SLC6A4 (0.52) | SLC6A4SLC6A3ADRB2TSHRMAPK1 | |
| SCHEMBL1145645 | 0.77 | ADRB2 (0.52) | SLC6A4SLC6A3ADRB2TSHRMAPK1 | |
| SCHEMBL9535658 | 0.75 | ADRB2 (0.44) | SLC6A4SLC6A3ADRB2TSHRMAPK1 | |
| SCHEMBL3956655 | 0.75 | TSHR (0.46) | SLC6A4SLC6A3TSHRTDP1LMNA | |
| Ammonia Solution, Strong SCHEMBL7978172 | 0.72 | ADRB2 (0.59) | SLC6A4SLC6A3ADRB2TSHRMAPK1 | |
| SCHEMBL19970042 | 0.72 | IDO1 (0.53) | SLC6A4SLC6A3ADRB2TSHRTDP1 | |
| SCHEMBL18681398 | 0.72 | ADRB2 (0.46) | SLC6A4SLC6A3ADRB2TSHRMAPK1 | |
| SCHEMBL197810 | 0.71 | ADRB2 (0.65) | SLC6A3ADRB2TSHRMAPK1HIF1A | |
| SCHEMBL17553335 | 0.70 | ADRB2 (0.56) | SLC6A4SLC6A3ADRB2TSHRMAPK1 | |
| SCHEMBL17429844 | 0.70 | SLC6A4 (0.66) | SLC6A4SLC6A3ADRB2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117168-A | ANTIFUNGAL DI(ARYL)METHYL ALKYL SULFONES | PPG INDUSTRIES, INC. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4103031-A | Control of plant pests with bis(4-chlorophenyl)methyl methyl sulfoxide | PPG INDUSTRIES, INC. (US) | 1978-07-25 | — | — | US | disclosed |
| US-4084005-A | Control of the harmful effects of Fusarium upon plants | PPG INDUSTRIES, INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4067909-A | FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |
| US-4064178-A | PESTICIDE, FUNGICIDE, BACTERICIDE | PPG INDUSTRIES, INC. (US) | 1977-12-20 | — | — | US | disclosed |