Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28767407 | 0.97 | ADRB2 (0.62) | ADRB2LMNACYP2A6TSHRMAPK1 | |
| SCHEMBL4445207 | 0.97 | ADRB2 (0.62) | ADRB2LMNACYP2A6TSHRMAPK1 | |
| SCHEMBL30720007 | 0.97 | ADRB2 (0.62) | ADRB2LMNACYP2A6TSHRMAPK1 | |
| Hydrogen Peroxide SCHEMBL10348371 | 0.94 | ADRB2 (0.59) | ADRB2LMNACYP2A6TSHRMAPK1 | |
| SCHEMBL12591826 | 0.91 | ADRB2 (0.56) | ADRB2LMNACYP2A6TSHRMAPK1 | |
| SCHEMBL104124 | 0.86 | TYR (0.58) | ADRB2LMNAMAPK1HIF1ATP53 | |
| SCHEMBL24616595 | 0.84 | ADRB2 (0.50) | ADRB2LMNACYP2A6TSHRMAPK1 | |
| SCHEMBL5866580 | 0.84 | NFKB1 (0.57) | ADRB2LMNAPOLBMEN1RAB9A | |
| SCHEMBL9876894 | 0.84 | ADRB2 (0.50) | ADRB2LMNATSHRMAPK1HIF1A | |
| SCHEMBL8297380 | 0.84 | MAOA (0.60) | ADRB2TSHRMAPK1HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2541 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117816241-A | Palladium-containing catalyst, preparation method and application thereof, and Suzuki-Miyaura reaction method | 中国石油化工股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-115477569-A | Preparation method of 4,4' -diisopropyl biphenyl | 北京格林凯默科技有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-114487184-A | Method for measuring 2 beta-carbomethoxy-3 beta- (4-chlorphenyl) tropane and related substances thereof | 江苏省原子医学研究所 | 2022-05-13 | — | — | CN | claimed |
| CN-109734959-B | Temperature-resistant free radical initiator and preparation method and application thereof | 清远市普塞呋磷化学有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-109761757-A | A kind of synthetic method of chlorophenesic acid | 山东润博生物科技有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-109734959-A | A kind of heat-resistance type radical initiator and its preparation method and application | 清远市普塞呋磷化学有限公司 | 2019-05-10 | — | — | CN | claimed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | claimed |
| US-9670208-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-06-06 | — | — | US | claimed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | claimed |
| CN-1314456-C | Medicament box of 2beta-[N,N'-di(2-mercaptoethyl) ethylene diamine] methyl-3 beta-(4- chlorphenyl) tropane | JIANGSU INST OF ATOMIC MEDICIN (CN) | 2007-05-09 | — | — | CN | claimed |
| US-20070100141-A1 | SUBSTITUTED PIPERAZINES AND PIPERIDINES AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-03 | — | — | US | claimed |
| WO-2006043260-A2 | ORALLY EFFECTIVE CANNABINOID ANALOGS | PHARMOS CORPORATION (US) | 2006-04-27 | — | — | WO | claimed |
| EP-1469842-A4 | BICYCLIC CB2 CANNABINOID RECEPTOR LIGANDS | PHARMOS CORP (US) | 2006-04-26 | — | — | EP | claimed |
| CN-1762499-A | Medicament box of 2beta-[N,N'-di(2-mercaptoethyl) ethylene diamine] methyl-3 beta-(4- chlorphenyl) tropane | JIANGSU INST OF ATOMIC MEDICIN (CN) | 2006-04-26 | — | — | CN | claimed |
| JP-2005523259-A | — | — | 2005-08-04 | — | — | JP | claimed |
| US-20050020544-A1 | Bicyclic CB2 cannabinoid receptor ligands | PHARMOS CORPORATION | 2005-01-27 | — | — | US | claimed |
| EP-1469842-A2 | BICYCLIC CB2 CANNABINOID RECEPTOR LIGANDS | PHARMOS CORPORATION (US) | 2004-10-27 | — | — | EP | claimed |
| WO-2003063758-A2 | BICYCLIC CB2 CANNABINOID RECEPTOR LIGANDS | PHARMOS CORPORATION (US) | 2003-08-07 | — | — | WO | claimed |
| WO-2003064359-A1 | BICYCLIC CB2 CANNABINOID RECEPTOR LIGANDS | PHARMOS CORPORATION (US) | 2003-08-07 | — | — | WO | claimed |