Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313519 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRMAOBCYP2A6LMNA | |
| SCHEMBL3848082 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRMAOBCYP2A6LMNA | |
| SCHEMBL12261578 | 0.72 | MAPT (0.58) | ALDH1A1MAOBLMNAHDAC3TNKS | |
| SCHEMBL869685 | 0.72 | MAPT (0.58) | ALDH1A1MAOBLMNAHDAC3TNKS | |
| SCHEMBL21268022 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRMAOBCYP2A6LMNA | |
| SCHEMBL7520233 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRMAOBCYP2A6PAM | |
| SCHEMBL142531 | 0.71 | HDAC1 (0.56) | ALDH1A1TSHRMAOBCYP2A6PAM | |
| Styrene SCHEMBL4259704 | 0.69 | ALDH1A1 (0.93) | ALDH1A1TSHRMAOBCYP2A6LMNA | |
| SCHEMBL176636 | 0.69 | MAPT (0.48) | ALDH1A1TSHRMAOBCYP2A6PAM | |
| SCHEMBL924820 | 0.69 | MAOB (0.43) | ALDH1A1TSHRMAOBCYP2A6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148995-A | FROM AN AZETIDINONE AND A FURANONE, MULTISTEP | Petrzilka, Theodor (CH) | 1979-04-10 | — | — | US | claimed |
| CN-101386694-B | Radiation resistant resin composition and radiation-proof wire/cable | FUJIKURA LTD | 2011-11-09 | — | — | CN | disclosed |
| CN-101386694-A | Radiation resistant resin composition and radiation-proof wire/cable | FUJIKURA LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| US-4148995-A | FROM AN AZETIDINONE AND A FURANONE, MULTISTEP | Petrzilka, Theodor (CH) | 1979-04-10 | — | — | US | disclosed |