SCHEMBL924820

SCHEMBL924820

[CH]([C](c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ AKR1C1 Q04828 1/20 0.43
▸ PLIN1 O60240 1/20 0.43
▸ BCHE P06276 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ TNFRSF1A P19438 1/20 0.43
▸ ACHE P22303 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ PLIN5 Q00G26 1/20 0.43
▸ CYP1B1 Q16678 1/20 0.43
▸ ABHD5 Q8WTS1 1/20 0.43
▸ ALDH1A1 P00352 4/20 0.39
▸ TSHR P16473 2/20 0.39
▸ CES2 O00748 2/20 0.39
▸ CES1 P23141 2/20 0.39
▸ DAO P14920 1/20 0.39
▸ NAPRT Q6XQN6 1/20 0.39
▸ CYP2A6 P11509 1/20 0.39
▸ NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893710 0.74 CYP1B1 (0.61) MAOBLMNAAKR1C1PLIN1BCHE
SCHEMBL3848015 0.74 CYP1B1 (0.61) MAOBLMNAPLIN1BCHEMAPT
SCHEMBL3848082 0.74 ALDH1A1 (0.42) MAOBLMNAAKR1C1PLIN1BCHE
SCHEMBL3848018 0.74 CYP1B1 (0.61) MAOBLMNAPLIN1BCHEMAPT
SCHEMBL3851044 0.72 AKR1C1 (0.48) MAOBLMNAAKR1C1PLIN1BCHE
SCHEMBL3851043 0.72 AKR1C1 (0.48) MAOBLMNAAKR1C1PLIN1BCHE
SCHEMBL12483197 0.70 ALOX15 (0.41) MAOBLMNAAKR1C1PLIN1BCHE
SCHEMBL12483194 0.70 ALOX15 (0.41) MAOBLMNAAKR1C1PLIN1BCHE
SCHEMBL11573032 0.69 ALDH1A1 (0.48) MAOBLMNAPLIN1MAPTRECQL
SCHEMBL21268022 0.69 ALDH1A1 (0.46) MAOBLMNAPLIN1MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 — — US claimed
US-20190177469-A1 CURABLE RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2019-06-13 — — US claimed
EP-1412309-B1 EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEM CO (US) 2015-04-29 — — EP claimed
EP-1412309-A2 EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 2004-04-28 — — EP claimed
US-6693219-B2 PREVENTING FLUOROPHOSPHITE LIGANDS HYDROLYSIS BY ADDING AN EPOXIDE; CATALYTIC HYDROFORMYLATION OF ALPHA-OLEFIN, HYDROGEN, CARBON MONOXIDE FOR PRODUCING ALDEHYDES EASTMAN CHEMICAL COMPANY 2004-02-17 — — US claimed
US-20030018220-A1 Preventing fluorophosphite ligands hydrolysis by adding an epoxide; catalytic hydroformylation of alpha-olefin, hydrogen, carbon monoxide for producing aldehydes EASTMAN CHEMICAL COMPANY 2003-01-23 — — US claimed
WO-2002098825-A2 EPOXIDE STABILIZATION OF FLUOROPHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 2002-12-12 — — WO claimed
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 — — US disclosed
US-20220325036-A1 PROCESS FOR THE PREPARATION OF POLYESTERS WITH RECYCLED MONOMERS FROM PYROLYSIS AND METHANOLYSIS EASTMAN CHEMICAL COMPANY (US) 2022-10-13 — — US disclosed
US-20220281793-A1 RECYCLE CONTENT (C4)ALKANAL EASTMAN CHEMICAL COMPANY (US) 2022-09-08 — — US disclosed
EP-4003950-A1 RECYCLE CONTENT (C4)ALKANOIC ACID Eastman Chemical Company (US) 2022-06-01 — — EP disclosed
EP-4003948-A1 RECYCLE CONTENT (C4)ALKANAL Eastman Chemical Company (US) 2022-06-01 — — EP disclosed
WO-2021021849-A1 RECYCLE CONTENT (C4)ALKANOIC ACID EASTMAN CHEMICAL COMPANY (US) 2021-02-04 — — WO disclosed
US-20040054211-A1 Process for reducing fluoride impurities resulting from use of fluorophosphite catalysts EASTMAN CHEMICAL COMPANY 2004-03-18 — — US disclosed
US-6693219-B2 PREVENTING FLUOROPHOSPHITE LIGANDS HYDROLYSIS BY ADDING AN EPOXIDE; CATALYTIC HYDROFORMYLATION OF ALPHA-OLEFIN, HYDROGEN, CARBON MONOXIDE FOR PRODUCING ALDEHYDES EASTMAN CHEMICAL COMPANY 2004-02-17 — — US disclosed
EP-1017494-B1 HYDROFORMYLATION PROCESS USING NOVEL PHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEM CO (US) 2004-01-21 — — EP disclosed
US-20030018220-A1 Preventing fluorophosphite ligands hydrolysis by adding an epoxide; catalytic hydroformylation of alpha-olefin, hydrogen, carbon monoxide for producing aldehydes EASTMAN CHEMICAL COMPANY 2003-01-23 — — US disclosed
EP-1017494-A1 HYDROFORMYLATION PROCESS USING NOVEL PHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 2000-07-12 — — EP disclosed
WO-1999013984-A1 HYDROFORMYLATION PROCESS USING NOVEL PHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 1999-03-25 — — WO disclosed
US-5840647-A Hydroformylation process using novel phosphite-metal catalyst system EASTMAN CHEMICAL COMPANY (US) 1998-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018220-A1 Preventing fluorophosphite ligands hydrolysis by adding an epoxide; catalytic hydroformylation of alpha-olefin, hydrogen, carbon monoxide for producing aldehydes CYP2F1, CYP4F2, CYP4F11 MAOB 230/4885LMNA 3994/4885AKR1C1 467/4885
US-20040054211-A1 Process for reducing fluoride impurities resulting from use of fluorophosphite catalysts PPIP5K2, PFAS, NSF MAOB 826/4885LMNA 1347/4885AKR1C1 3866/4885
US-20220281793-A1 RECYCLE CONTENT (C4)ALKANAL ALKBH3, AKR1C4, CBR1 MAOB 1470/4885LMNA 1467/4885AKR1C1 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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