Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PYGB | P11216 | 6/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573190 | 1.00 | LMNA (0.52) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| SCHEMBL29572633 | 1.00 | LMNA (0.52) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL11409480 | 0.91 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL8539 | 0.91 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL11409484 | 0.91 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL1648834 | 0.91 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL19520816 | 0.90 | LMNA (0.63) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL10424026 | 0.85 | LMNA (0.78) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| SCHEMBL11432138 | 0.83 | PYGB (0.54) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| SCHEMBL11425370 | 0.83 | PYGB (0.54) | LMNAKDM4ECYP2D6CYP2C19ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54144319-A | — | — | None | — | — | JP | disclosed |
| JP-S54144319-A | NOVEL AMINOGLUCOPYRANOSIDE DERIVATIVE ITS PREPARATION, AND ONCOSTATIC DRUGS COMPRISING IT AS ACTIVE CONSTITUENT | KAKEN PHARMACEUT CO LTD | 1979-11-10 | — | — | JP | disclosed |