Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573090 | 0.81 | — | — | |
| SCHEMBL11571857 | 0.79 | GAA (0.40) | MEN1POLBKMT2ATP53GAA | |
| SCHEMBL11814647 | 0.76 | EGFR (0.41) | MEN1KMT2AGAA | |
| SCHEMBL11813822 | 0.70 | EGFR (0.36) | POLBKMT2AGAA | |
| SCHEMBL11575096 | 0.68 | — | — | |
| SCHEMBL11816178 | 0.67 | MEN1 (0.40) | MEN1POLBKMT2AGAA | |
| SCHEMBL11809306 | 0.67 | L3MBTL1 (0.45) | POLBKMT2AGAA | |
| SCHEMBL11813332 | 0.64 | RECQL (0.41) | MEN1POLBKMT2A | |
| SCHEMBL11817170 | 0.63 | EPHX1 (0.30) | — | |
| SCHEMBL11808277 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071627-A | 2-Oximino-tetrahydro-1,4-thiazin-5-one compounds and pesticidal carbamate derivatives | UNION CARBIDE CORPORATION (US) | 1978-01-31 | — | — | US | disclosed |