Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814647 | 0.92 | EGFR (0.41) | EGFRKDRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11809306 | 0.89 | L3MBTL1 (0.45) | EGFRKDRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11813332 | 0.87 | RECQL (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19NPSR1 | |
| SCHEMBL11816178 | 0.81 | MEN1 (0.40) | NPSR1GAALMNAKMT2AALDH1A1 | |
| SCHEMBL11816857 | 0.74 | — | — | |
| SCHEMBL11818218 | 0.72 | TYMP (0.30) | ALDH1A1 | |
| SCHEMBL11813340 | 0.70 | TYMP (0.33) | — | |
| SCHEMBL11574262 | 0.70 | MEN1 (0.30) | GAAKMT2APOLB | |
| SCHEMBL11573090 | 0.69 | — | — | |
| SCHEMBL11814661 | 0.66 | TYMP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966953-A | 2-(Carbamoyloximino)-4-thiazolidinone compounds as insecticidal, miticidal or nematocidal agents | UNION CARBIDE CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |