Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813822 | 0.87 | EGFR (0.36) | RECQLLMNAKMT2AALDH1A1ATM | |
| SCHEMBL11814647 | 0.85 | EGFR (0.41) | RECQLLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL11809306 | 0.84 | L3MBTL1 (0.45) | LMNAKMT2AALDH1A1MAPTATM | |
| SCHEMBL11816178 | 0.79 | MEN1 (0.40) | LMNAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL11820453 | 0.78 | RECQL (0.48) | RECQLLMNAKMT2AALDH1A1MAPT | |
| SCHEMBL11820448 | 0.78 | RECQL (0.48) | RECQLLMNAKMT2AALDH1A1MAPT | |
| SCHEMBL11751042 | 0.70 | PARP1 (0.33) | — | |
| SCHEMBL2633830 | 0.69 | ALDH1A1 (0.58) | RECQLLMNAKMT2AALDH1A1MAPT | |
| SCHEMBL11817635 | 0.68 | — | — | |
| SCHEMBL11573090 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966953-A | 2-(Carbamoyloximino)-4-thiazolidinone compounds as insecticidal, miticidal or nematocidal agents | UNION CARBIDE CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |