Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576587 | 0.93 | HDAC6 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL17685267 | 0.83 | ADRA2C (0.48) | MAPK1SMN1; SMN2ADRA2CALDH1A1MAPT | |
| SCHEMBL11335716 | 0.81 | HDAC6 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13571480 | 0.81 | HPGD (0.57) | HDAC3HDAC1HDAC2HDAC6ADRA2C | |
| SCHEMBL5153394 | 0.80 | HDAC6 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10903602 | 0.79 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL13571558 | 0.78 | CES2 (0.53) | HDAC1HDAC6ALDH1A1GAAHPGD | |
| SCHEMBL27834756 | 0.78 | CES2 (0.53) | HDAC1HDAC6ALDH1A1GAAHPGD | |
| SCHEMBL9065743 | 0.78 | ADRA2C (0.58) | ADRA2CMAPTL3MBTL1LMNATDP1 | |
| SCHEMBL27834759 | 0.78 | CES2 (0.53) | HDAC1HDAC6ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166184-A | 2H-IMIDAZOLE-2-THIONE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-08-28 | — | — | US | disclosed |