SCHEMBL11575247

SCHEMBL11575247

O=C1C=CC(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
HSD17B3 P37058 1/20 0.42
PDE4B Q07343 2/20 0.40
CDC25B P30305 2/20 0.40
IDO1 P14902 1/20 0.40
AKT1 P31749 1/20 0.40
SNCA P37840 1/20 0.40
MAP2K1 Q02750 1/20 0.40
PIN1 Q13526 1/20 0.40
EHMT2 Q96KQ7 1/20 0.40
NSD1 Q96L73 1/20 0.40
EHMT1 Q9H9B1 1/20 0.40
KMT2A Q03164 1/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 3/20 0.36
P2RX7 Q99572 1/20 0.36
FGFR1 P11362 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27490209 0.86 PDE4B (0.42) MAOAMAOBHSD17B3PDE4BCDC25B
SCHEMBL57764 0.85 MAOA (0.52) MAOAMAOBHSD17B3PDE4BCDC25B
Ammonia Solution, Strong SCHEMBL634924 0.82 MAOA (0.50) MAOAMAOBHSD17B3PDE4BCDC25B
Benzoquinone SCHEMBL20451202 0.78 MAOA (0.58) MAOAMAOBHSD17B3PDE4BCDC25B
SCHEMBL28232503 0.74 MAOA (0.43) MAOAMAOBHSD17B3PDE4BCDC25B
SCHEMBL25834626 0.74 MAOA (0.48) MAOAMAOBHSD17B3PDE4BCDC25B
SCHEMBL27522731 0.74 MAOA (0.43) MAOAMAOBHSD17B3PDE4BCDC25B
SCHEMBL9618394 0.74 P2RX7 (0.48) MAOAMAOBHSD17B3PDE4BCDC25B
SCHEMBL27907707 0.74 MAOA (0.43) MAOAMAOBHSD17B3PDE4BCDC25B
SCHEMBL14663757 0.73 ALDH1A1 (0.38) PDE4BKMT2AMAPTHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146515-A Organic silicon porous polymer material and preparation method and application thereof 齐鲁工业大学(山东省科学院) 2024-06-07 CN disclosed
CN-104151150-B A kind of preparation method of 3,4-bis-(3,4,5-trifluorophenyl)-2,5-diphenyl cyclopentadienone 山东大学 2016-08-24 CN disclosed
US-4100046-A Radiation polymerizable cycloalkenyl derivatives of acrylated epoxidized fatty oils or fatty acids UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed