Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644380 | 0.78 | PKM (0.45) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL4644373 | 0.78 | PKM (0.45) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL5991929 | 0.76 | ALDH1A1 (0.74) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL8499131 | 0.74 | ALDH1A1 (0.71) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL7727868 | 0.73 | PKM (0.70) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL15989159 | 0.73 | ALDH1A1 (0.69) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL27395266 | 0.72 | ALDH1A1 (1.00) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL7024490 | 0.72 | PKM (0.68) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL866120 | 0.72 | PKM (0.68) | ALDH1A1RECQLATMPKMTHRB | |
| SCHEMBL8499822 | 0.72 | HTT (0.69) | ALDH1A1RECQLATMPKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1907962-A | Process for preparing diethyl 2-acetamido-2-(3-(2-phenylhydrazono)propyl)malonate | SHANGHAI CHEMICAL REAGENT RES (CN) | 2007-02-07 | — | — | CN | disclosed |
| US-4084057-A | Process for the production of 4-acylamido-4, 4-dicarbalkoxy-butanalphenylhydrazone | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1978-04-11 | — | — | US | disclosed |