Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | MMP13 | P45452 | 9/20 | 0.51 |
| ▸ | MMP1 | P03956 | 7/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195254 | 0.81 | PKM (0.61) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL9732631 | 0.79 | PKM (0.59) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL751678 | 0.79 | PKM (0.59) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL11758605 | 0.79 | CA12 (0.59) | PKMCA1CA2GAARAB9A | |
| SCHEMBL7411621 | 0.78 | MMP13 (0.57) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL11764911 | 0.76 | CA12 (0.62) | MMP13MMP1CA1CA2MMP2 | |
| SCHEMBL27694463 | 0.76 | GAA (0.54) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL4303010 | 0.76 | PKM (0.67) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL21818 | 0.76 | GAA (0.54) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL13074716 | 0.75 | PKM (1.00) | PKMMMP13MMP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117168-A | ANTIFUNGAL DI(ARYL)METHYL ALKYL SULFONES | PPG INDUSTRIES, INC. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4103031-A | Control of plant pests with bis(4-chlorophenyl)methyl methyl sulfoxide | PPG INDUSTRIES, INC. (US) | 1978-07-25 | — | — | US | disclosed |
| US-4084005-A | Control of the harmful effects of Fusarium upon plants | PPG INDUSTRIES, INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4067909-A | FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |
| US-4064178-A | PESTICIDE, FUNGICIDE, BACTERICIDE | PPG INDUSTRIES, INC. (US) | 1977-12-20 | — | — | US | disclosed |