SCHEMBL11575349

SCHEMBL11575349

CC(=O)CCOS(=O)(=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.41
MAPK1 P28482 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
HSD11B1 P28845 4/20 0.40
PARL Q9H300 1/20 0.40
BCAT1 P54687 1/20 0.40
PSIP1 O75475 1/20 0.39
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11301339 0.85 TBXA2R (0.44) ALDH1A1MAPTMAPK1LMNAHSD11B1
SCHEMBL14730788 0.84 MAPT (0.43) ALDH1A1POLBMAPTMAPK1KMT2A
SCHEMBL17763488 0.84 STAT3 (0.47) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL28134943 0.83 CA12 (0.47) ALDH1A1POLBMAPTMAPK1KMT2A
SCHEMBL15669777 0.82 ALDH1A1 (0.49) ALDH1A1MAPTMAPK1PARLSMN1; SMN2
SCHEMBL11747444 0.81 POLB (0.44) ALDH1A1POLBMAPTMAPK1KMT2A
SCHEMBL12540064 0.81 ALDH1A1 (0.46) ALDH1A1POLBMAPK1KMT2AHSD11B1
SCHEMBL14778910 0.81 PARL (0.47) ALDH1A1MAPTMAPK1KMT2ALMNA
SCHEMBL5945104 0.81 PARL (0.47) ALDH1A1MAPTMAPK1KMT2ALMNA
SCHEMBL3449015 0.80 PARL (0.50) ALDH1A1MAPTMAPK1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4128728-A Production of 2,3,6-trimethylphenol BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) 1978-12-05 US claimed
US-4128728-A Production of 2,3,6-trimethylphenol BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed