Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PARL | Q9H300 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890353 | 0.90 | ALDH1A1 (0.41) | TBXA2RALDH1A1LMNAPARLKEAP1 | |
| SCHEMBL15669777 | 0.89 | ALDH1A1 (0.49) | TBXA2RALDH1A1PARLSMN1; SMN2MAPK1 | |
| SCHEMBL11575349 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNAPARLHSD11B1SMN1; SMN2 | |
| SCHEMBL5792946 | 0.84 | L3MBTL1 (0.54) | TBXA2RALDH1A1LMNAKEAP1TSHR | |
| SCHEMBL3449015 | 0.83 | PARL (0.50) | ALDH1A1PARLSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL28134943 | 0.82 | CA12 (0.47) | ALDH1A1LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL14730788 | 0.80 | MAPT (0.43) | ALDH1A1PARLHSD11B1SMN1; SMN2TSHR | |
| SCHEMBL30555660 | 0.80 | PARL (0.44) | ALDH1A1PARLSMN1; SMN2TSHRMAPT | |
| SCHEMBL3447513 | 0.80 | PARL (0.44) | ALDH1A1PARLSMN1; SMN2TSHRMAPT | |
| SCHEMBL9243189 | 0.80 | ALOX15 (0.47) | TBXA2RALDH1A1PARLHSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014070092-A1 | FUNCTIONALIZED CELLULOSE NANOCRYSTALS, A METHOD FOR THE PREPARATION THEREOF AND USE OF FUNCTIONALIZED CELLULOSE NANOCRYSTALS IN COMPOSITES AND FOR GRAFTING | SWETREE TECHNOLOGIES AB (SE) | 2014-05-08 | — | — | WO | disclosed |
| EP-0050327-A1 | Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1982-04-28 | — | — | EP | disclosed |